| Research into manic depression, more
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| | less behavior traits that could be called
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| formally called bipolar disorder, has
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| | despair-type behavior. These mice
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| been hindered, according to many in the
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| | without the GluR6 also displayed more
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| scientific community due to the lack of
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| | aggressive behavior, another character
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| animal models upon which to base studies.
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| | trait of a manic episode of manic
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| Until now that is. Scientists have been
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| | depression.
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| able to create a genetically engineered
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| | The scientists also administered
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| defect in a specific gene which may play
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| | biochemical tests on these mice, the
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| a leading role in causing mood disorders,
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| | results of which suggested that the GluR6
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| like manic depression. The gene is known
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| | gene may also play a unique role in
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| as glutamate receptor 6 - referred to as
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| | actually regulating some of the symptoms
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| GluR6 - and has long been associated with
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| | of mania.
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| manic depression.
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| | Now that researchers have genetically
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| Scientists knew that the gene was related
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| | engineered this type of laboratory mouse,
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| to manic depression but were unsure of
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| | they'll be better able to study manic
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| the exact mechanism. Not only that, but
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| | depression. This study also opens the
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| the gene encoding for the GluR6 receptor
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| | door for further studies that may very
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| has not only been linked to manic
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| | well lead to new treatments.
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| depression, but also to the tendency of
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| | Manic depression is a mental health
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| some individuals to consider suicide
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| | disorder characterized by erratic swings
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| while taking antidepressant drugs in a
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| | in mood. Individuals with this health
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| separate pharmacogenetic study.
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| | issue, most recently renamed bipolar
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| Interestingly enough, individuals who
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| | disorder, are subject not only to
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| suffer with manic depression are the most
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| | depression, but also episodes of mania.
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| susceptible to antidepressant-induced
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| | These manic episodes involve high energy
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| states of restlessness.
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| | expenditure, sleeplessness for several
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| In the new study, scientists utilized
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| | days sometimes, as well as rapid speech,
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| mice to further examine the issue. The
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| | racing thoughts and feelings of
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| scientists used mice with the GluR6 gene
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| | grandiosity. Those individuals
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| missing, comparing them to a control
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| | experiencing a manic episode may also
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| group of mice who had the gene.
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| | display psychotic behavior, such as
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| Both groups of mice underwent a series of
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| | hallucinations.
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| tests specifically created to imitate the
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| | Several mood stabilizing drugs are
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| symptoms of manic episode of manic
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| | currently available for the treatment of
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| depression. The researchers discovered
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| | manic depression. Individuals with manic
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| that the mice with the Glu6R gene missing
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| | depression are also encouraged to take a
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| displayed many of the symptoms of mania.
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| | series of behavioral therapy as well.
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| Not only were these mice more active in
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| | For more resources regarding bipolar or
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| several tests, they also displayed more
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| | even about symptom of bipolar disorder
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| anxiety and more behavior traits that
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| | and especially about bipolar medication
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| could be classified as risk taking and
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| | please review these pages.
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