| The treatment of Anxiety Disorders and Panic | | | | the brain's own safety signal. They report on their |
| Attacks has engaged many doctors and researchers | | | | findings in the November 7, 2002 issue of the Nature |
| with mixed success, but some experiments on rats | | | | publication. |
| have given some useful pointers to the use of the | | | | Dr Quirk explained that repeated exposure to |
| Amygdala Gland and how it can be re-programmed to | | | | traumatic reminders without any adverse |
| alleviate anxiety disorders and panic attacks. | | | | consequences causes those fear responses to |
| Researchers who were funded by the National | | | | gradually disappear. This reduction of fear appears to |
| Institute of Mental Health (NIMH) have discovered a | | | | be an active rather than passive process, So it doesn't |
| new high tech way to quell panic in rats. They have | | | | erase the fear association from memory, but |
| detected the brain's equivalent of an 'all clear' signal, | | | | generates a new memory for safety purposes |
| that, when simulated, reduces the effects of fear, and | | | | The researchers recorded electrical activity of neurons |
| can even eliminate it altogether. This discovery could | | | | in the prefrontal cortex as rats were fear-conditioned |
| lead to physiological treatments for extreme fear | | | | by teaching them to fear a sound by repeatedly |
| responses seen in anxiety disorders that would not | | | | pairing it with an electrical shock. Then they abolished |
| require any medication. | | | | this conditioned fear by presenting the sound without |
| Rats normally freeze with fear when they hear a tone | | | | the shock; the animals no longer froze when they |
| they have been conditioned to associate with an | | | | heard the tone. The part of the brain that was |
| electric shock. Dr. Gregory Quirk and Mohammed | | | | conditioned to stop the anxiety is the Amygdala Gland, |
| Milad, from the Ponce School of Medicine in Puerto | | | | and this treatment has been found to be very |
| Rico, have now demonstrated that stimulating a part | | | | successful in treating anxiety and panic attacks in |
| of the front area of the brain known as the prefrontal | | | | humans. |
| cortex, extinguishes this fear response by mimicking | | | | |