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Article #66: Clinical Depression - Causes, Symptoms and Treatment

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Clinical depression (also called major 1. Persistent feelings of sadness,
depressive disorder, or unipolar irritability, or anxiety
depression when compared to bipolar 2. Overreaction to irritations
disorder) is a state of intense sadness, 3. Loss of interest in activities
melancholia or despair that has advanced previously enjoyed, including sex
to the point of being disruptive to an 4. Sleeping too much, sleeping too little
individual's social functioning and/or 5. Losing or gaining weight.
activities of daily living. Depression Treatment of Clinical Depression
affects people differently. Some feel Medication that relieves the symptoms of
down for extended periods of time; for depression has been available for several
others the feelings of depression come decades such as citalopram (Celexa),
and go. Depression is a mood disorder fluoxetine (Prozac), paroxetine (Paxil),
that causes you to feel sad or hopeless and sertraline (Zoloft). Under some
for an extended period of time. More than circumstances, medication and
just a bout of "the blues" or temporary psychotherapy may be more effective than
feelings of grief or low energy. Many either treatment separately. Family of
people identify the feeling of being drugs includes fluoxetine (Prozac),
clinically depressed as "feeling sad for paroxetine (Paxil), escitalopram
no reason", or "having no motivation to (Lexapro), citalopram (Celexa), and
do anything." One suffering from sertraline (Zoloft). These
depression may feel tired, sad, antidepressants typically have fewer
irritable, lazy, unmotivated, and adverse side effects than the tricyclics
apathetic. or the MAOIs, although such effects as
Clinical depression is not just grief or drowsiness, dry mouth, nervousness,
sadness. Clinical depression is anxiety, insomnia, decreased appetite,
generally acknowledged to be more serious and decreased ability to function
than normal depressed feelings. It often sexually may occur.
leads to constant negative thinking and Serotonin-norepinephrine reuptake
sometimes substance abuse. Extreme inhibitors (SNRIs) such as venlafaxine
depression can culminate in its sufferers (Effexor) and duloxetine (Cymbalta) are a
attempting or committing suicide. There newer form of antidepressant that works
are three main types of depression; on both norepinephrine and 5-HT.Selective
unipolar disorder (major depression), serotonin reuptake inhibitors (SSRIs) are
bipolar disorder (manic depression) and medications that increase the amount of
dysthymia (prolonged sadness). Major the neurochemical serotonin in the brain.
depression usually strikes people between Norepinephrine (noradrenaline) reuptake
the ages of 25 and 44, although it can inhibitors (NRIs) such as reboxetine
affect any person at any age. For most (Edronax) act via norepinephrine (also
people, episodes of major depression last known as noradrenaline). Tricyclic
from six to nine months. Feelings of antidepressants are the oldest and
total indestructibility are common, and include such medications as amitriptyline
the manic person may believe for example and desipramine. Tricyclics block the
that not even moving cars can stop him or reuptake of certain neurotransmitters
her, or that he or she can fly. They such as norepinephrine (noradrenaline)
experience delusions and hallucinations and serotonin. They are used less
and sometimes talk so fast that their commonly now due to the development of
speech becomes illegible. more selective and safer drugs. Monoamine
Causes of Clinical Depression oxidase inhibitors (MAOIs) such as
1. Genetic Predisposition (Hormonal phenelzine (Nardil) may be used if other
imbalance ). antidepressant medications are
2. Medical conditions (Neurochemical ). ineffective. Because there are
3. Dietary . potentially fatal interactions between
4. Alcohol and other drugs. this class of medication and certain
5. Sleep quality. foods, particularly those containing
6. Certain styles of thinking. Tyramine. electroconvulsive therapy, are
Symptoms of Clinical Depression used in severe cases.






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